Feb 2019: We published the first application of our novel, directional signaling measure to brain data from patients with Alzheimer's disease (AD). We found that specific routes of directional signaling, or effective connectivity, are disrupted in the default mode network of patients. This approach, based on simultaneous PET/MR imaging, might offer a link to molecular spreading theories of AD-pathology in the human brain. 

Please find the publication in the journal Human Brain Mapping, title: Effective connectivity in the default mode network is distinctively disrupted in Alzheimer's disease—A simultaneous resting‐state FDG‐PET/fMRI study by Scherr et al.

 

Oct 2018: Katarzyna established metabolic imaging of GABA and glutamate in my lab and published important work on the dynamics of these neurotransmitters in the human brain. You can find the paper in the Journal of Neuroscience: Opposite dynamics of GABA and glutamate levels in the occipital cortex during visual processing.

Here's some press coverage of our work on GABA/glutamate signaling in the human brain.

Jun 2018: Gabriel Castrillon will give a talk on "Inhibitory TMS differentially affects brain network communication depending on the stimulation site" during OHBM 2018 in Singapore. Schedule: Tue, June 19, Session: Brain Stimulation Methods 

Feb 2018: During the next 5 years, Valentin will apply novel methods and simultaneous PET/MRI brain imaging to track memory consolidation in the human brain. ERC grants are prestigious funding from the European Research Council of the EU. 

News from TUM: in german; in english 

Dec 2017: Katarzyna Kurcyus did a great job during her PhD-period in my lab and successfully submitted her PhD thesis "Using magnetic resonance spectroscopy to study neural activity: The role of inhibitory and excitatory neurotransmitters for systems-level brain dynamics"